S. Said Primary Author S. Anwar Primary Author W.P.B. Putra Primary Author P.P. Agung Primary Author mixed material bibliography 2019 en English

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Bovine growth hormone receptor (bGHR) gene was one of the growth hormone family genes that important for body growth and development of cattle. This research was carried out to identify the polymorphism in the exon 10 of bGHR gene from 142 heads of Pasundan cows at West Java and its association with body length (BL), withers height (WH), heart girth (HG), and body weight (BW). There are two mutation points in the bGHR gene based on the sequencing analysis i.e. g.3322del.A and g.3338A>G. The single nucleotide polymorphism (SNP) at g.3338A>G was detected using PCRRFLP method with AluI restriction enzyme and showed three genotypes of AA (0.49), AG (0.37), and GG (0.14). The allelic frequencies were 0.67 (A) and 0.33 (G). The number of allele effective (ne) value was 1.79 and described that A allele was the higher allele in the bGHR gene in this study. The polymorphic informative content (PIC) value was 0.34 and categorized as a moderate category. The Chi-square (χ2) analysis showed that the population sample was in the Hardy-Weinberg equilibrium (χ2 NONE 2615787 UPT. Perpustakaan UNIMUDA Sorong Universitas Pendidikan Muhammadiyah (UNIMUDA) Sorong P01650S My Library 2236 2021-07-31 08:31:56 2021-07-31 08:31:56 machine generated